ROLE OF THE MITOCHONDRION IN PROGRAMMED NECROSIS

ROLE OF THE MITOCHONDRION IN PROGRAMMED NECROSIS

ROLE OF THE MITOCHONDRION IN PROGRAMMED NECROSIS

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In contrast to the programmed Climbing Items nature of apoptosis and autophagy, necrotic cell death has always been believed to be a random, uncontrolled process that leads to the accidental death of the cell.This dogma, however, is being challenged and the concept of necrosis also being programmed is gaining ground.In particular, mitochondria appear to play a pivotal role in the mediation of programmed necrosis.

The purpose of this review, therefore, is to appraise the current concepts regarding the signaling mechanisms of programmed necrosis, with Brown Seaweed specific attention to the contribution of mitochondria to this process.

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